Septic arthritisis

Authors

Bryan Antonio Ramón Cáceres
Ivette Denisse Quinteros Sánchez
Susan Karina Ortega Castillo

Synopsis

Septic arthritisis considered a medical emergency characterizedby the colonization of bacteria in the joint space, resulting inintense inflammatory reactions that can lead to the total destructionof the articular cartilage and even the subchondral bone if not diagnosed andtreated in a timely manner. Its etiology is almost entirely bacterial in origin, with Staphylococcus aureus being the most common agent in adults andKingella kingae in the pediatric population. The incidence of this pathology ranges from 2to 12 cases per 100,000 inhabitants, increasing in the elderly,immunocompromised individuals, and joint prosthesis carriers.The cornerstone of diagnosis is arthrocentesis and microbiological analysis in the laboratory of the synovial fluid taken, supported by inflammatory biomarkers and imaging studies. The fundamental pillarfor diagnosis is arthrocentesis and microbiological analysis inthe laboratory of the synovial fluid taken, supported by inflammatory biomarkersand imaging studies. Treatment is based on the applicationof antibiotic therapy according to culture, joint drainage, and early rehabilitation. Recent studies reinforce the usefulness of molecular techniques(PCR and 16S rRNA) to improve the detection of pathogens that are difficultto culture. The prognosis depends on timely diagnosis and treatment. Adespite diagnostic and therapeutic advances, septic arthritis remainsa significant clinical challenge that requires ongoing research intodiagnostic and antimicrobial strategies.

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Published

April 21, 2026

How to Cite

Septic arthritisis. (2026). In INFECTOLOGÍA CLÍNICA TOMO 3 (pp. 15-28). Puerto Madero Editorial Académica. https://doi.org/10.55204/pmea.128.c188