ENFERMEDAD INFLAMATORIA PÉLVICA
Synopsis
Pelvic inflammatory disease (PID) is a disorder of the female upper genital tract characterized by inflammation and infection of the pelvic organs, with significant implications for reproductive health. This literature review, conducted under PRISMA guidelines, analyzed studies published between 2020 and 2025 regarding the etiology, diagnosis, and management of PID in women of reproductive age. The findings confirm a shift in the etiological paradigm: although historically attributed to Chlamydia trachomatis and Neisseria gonorrhoeae, PID is now recognized as a polymicrobial condition, with a significant role played by microorganisms associated with bacterial vaginosis (Atopobium vaginae, Sneathia spp., Megasphaera spp.) and emerging pathogens such as Mycoplasma genitalium. The latter increases the risk of developing PID by up to 67% and shows growing resistance to conventional antibiotics. Clinically, most patients are young, sexually active women presenting with pelvic pain, dyspareunia, and menstrual irregularities; however, the nonspecific nature of symptoms often hinders timely diagnosis. There is a clear need for accessible molecular testing, therapeutic regimens that include coverage for anaerobes and emerging microorganisms, and preventive strategies emphasizing sexual education and screening. Current evidence highlights PID as a complex, multifactorial, and persistent syndrome requiring continuous updates in clinical and therapeutic approaches to reduce complications such as infertility and chronic pelvic pain.
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