INTERVENCIÓN NUTRICIONAL EN ENFERMEDADES INFECCIOSAS INTESTINALES: MECANISMOS FISIOPATOLÓGICOS, EVIDENCIA CLÍNICA Y ESTRATEGIAS TERAPÉUTICAS ACTUALES
Synopsis
Intestinal infectious diseases are a leading cause of morbidity and mortality worldwide, especially in pediatric populations in developing countries. These diseases not only cause acute episodes of diarrhea and dehydration but also perpetuate a vicious cycle of malnutrition, chronic inflammation, and intestinal mucosal dysfunction. In this context, nutritional intervention represents an essential therapeutic tool aimed at the metabolic, structural, and immunological recovery of the bowel, as well as contributing to the restoration of the altered gut microbiota. The gut microbiota plays a key role in digestion, immune modulation, and resistance to pathogens. Diet exerts a determining influence on its composition: fermentable components and polyphenols promote beneficial bacteria that produce short-chain fatty acids, essential for epithelial integrity. In contrast, Western dietary patterns, rich in saturated fats and low in fiber, reduce microbial diversity and promote a chronic inflammatory state in the gut.
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