USO RACIONAL DE ANTIMICROBIANOS
Synopsis
The rational use of antimicrobials is based on the administration of these drugs under strict clinical criteria in appropriate doses and for appropriate durations, depending on the type of infection and the causative microorganism. The aim of this review is to promote the rational use of antimicrobials in order to optimize the treatment of infections, prevent drug resistance, and contribute to the improvement of global public health. Antimicrobial optimization programs have been implemented in healthcare centers, which can be adapted to the needs of each healthcare facility. It is estimated that the use of antimicrobials is inappropriate in up to 30% of cases, and their excessive use in outpatient settings is also noteworthy. Despite efforts to curb antimicrobial resistance, several limitations have been identified. Antimicrobial resistance is a global threat driven by inappropriate prescribing and the use of empirical therapy. The application of Clinical Practice Guidelines and programs promoting the Rational Use of Antimicrobials has proven effective in reducing expenditure and use. However, the use of broad-spectrum antimicrobials persists, and self-medication and academic/economic status also have an inappropriate influence.
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